For CAD identification, a number of well-established biomarkers have been used extensively, such as brain-type natriuretic peptide (BNP), cardiac troponin-I (cTnI), cardiac troponin-T (cTnT), myoglobin (Myo), creatine phosphokinase MB (CK-MB), and N-terminal proBNP (BNPT). The gene discussed is NPPB; the disease is coronary artery disorder.