Tumor size contribution that is 0 (i.e., in lesions ≤ 3 cm), 1 (in lesions 3 cm to 6 cm), and 4 points (i.e., in lesions ≥ 6 cm),Number of lesions contributes 0 points (i.e., ≤3 nodules) and 2 points (i.e., ≥4 nodules)AFP level contribution 0 points (i.e., ≤100 ng/mL), 2 points (i.e., 100–1000 ng/mL), and 3 points (i.e., ≥1000 ng/mL) respectively.Note that low-risk patients had ≤2 total score and high-risk patients had >2 total score. The gene discussed is AFP; the disease is neoplasm.