Helpful markers for studying ovarian tumors in children and adolescents include AFP for immature teratomas, yolk sac tumors, embryonal carcinoma, and Sertoli–Leydig cell tumors (rare); LDH for dysgerminomas; β-hCG for dysgerminomas (rare), embryonal carcinoma, and non-gestational choriocarcinoma; CA-125 for malignant epithelial tumors; and inhibin A and B for juvenile granulosa cell tumors [2]. The gene discussed is AFP; the disease is embryonal carcinoma.