The authors identified several CRF and CCT loci harbored within 1 Mb of mendelian genes associated with rare corneal or connective tissue diseases. These included FECD7, TCF4, SLC4A11, UBIAD1, MPV17, ZNF513, COL5A1, ZNF469, COL8A2, AGBL1, SMAD3, DCN, KERA, and TGFB2. This evidence concerns the gene ZNF469 and connective tissue disorder.