Other studies have reported a protective effect of vitamin D deficiency against the risk of HPT; for example, in a prospective observational study of 100 patients who underwent total thyroidectomy, individuals with vitamin D deficiency exhibited a lower rate of transient HPT, higher median PTH levels 24 h after surgery, and a smaller decline in postoperative PTH levels when compared to those without vitamin D deficiency [22]. The gene discussed is PTH; the disease is vitamin D deficiency.