AKI (acute kidney injury); RUNX1 (runt-related transcription factor 1); SNHG5 (small nuclear RNA host gene 5); TLR4/NF-ĸb (toll-like receptor 4/nuclear factor-ĸB); I/R (ischemia/reperfusion); DR6 (death receptor 6). The gene discussed is RUNX1; the disease is acute kidney injury.