In particular, in PTZ-induced or kainic acid-induced mouse models of epilepsy, the addition of the omega-3 fatty acids (such as docosapentaenoic acid and docosahexaenoic acid) to the diet was able to inhibit the binding of ASCs to NLRP3 and reduce the production of IL-1β, which effectively protects the mice from the effects of epilepsy [29, 33]. Here, IL1B is linked to epilepsy.