Another research in the mouse model of glioblastoma from the same institution showed similar findings, which were consistent with the in vitro and in vivo results, demonstrating a paradoxical 50% increase in immunosuppressive M2 macrophages (CD45+CD11b+F4/80+CD206+) and a concomitant decrease in pro-inflammatory M1 macrophages (CD45+CD11b+F4/80+CD80hi) due to KD [73]. The gene discussed is PTPRC; the disease is glioblastoma.