Variants in SCN1A give rise to a wide range of epilepsy syndromes, ranging from mild familial febrile seizures (FEB) [4], and genetic epilepsy with febrile seizures plus (GEFS +) [5], to severe developmental and epileptic encephalopathy (DEE) or Dravet syndrome (DS) [6–8]. The gene discussed is SCN1A; the disease is epilepsy.