Four different pancreatic cancer cell lines were orthotopically injected into NSG and NSG-HA mice for 5 weeks, and representative images of the tumors are shown in Fig. 6A and B. We found that AsPC-1 (TFhigh) cells grew significantly faster than its TF-negative control, AsPC-1 (TFKO) cells (Fig. 6C), whereas MIA PaCa-2 (TFlow) cells grew significantly slower than its TF-overexpressing counterpart, MIA PaCa-2 (TFhigh) cells (Fig. 6D). Here, TF is linked to pancreatic neoplasm.