EPM2A and myoclonic epilepsy: LD is caused by pathogenic genetic variants transmitted autosomal recessively from parents to offspring in either of two genes: EPM2A on chromosome 6q24 encoding laforin (myoclonic epilepsy of Lafora-1; MIM 254780) or NHLRC1/EPM2B on chromosome 6p22 encoding malin (myoclonic epilepsy of Lafora-2; MIM 620681) [6, 7].