Per 1-unit mRSS change (0–52 W), histologic parameters with the greatest associated changes were (OR, 95% CI, p-value): telangiectasia (2.01, [(1.31—3.07], 0.001), perivascular CD3 + (0.99, [0.97—1.02], 0.015), and % of CD8 + among CD3 + (0.95, [0.89—1.01], 0.031). The gene discussed is CD8A; the disease is Telangiectasia.