Per 1-unit mRSS change, the histological parameters with significant associated responses/changes (OR, 95% CI, p-value) were: telangiectasia = 2.01, [1.31—3.07], (p = 0.001); perivascular CD3 + lymphocytes = 0.99, [0.97—1.02], (p = 0.015); and % of CD8 + among CD3 + cell = 0.95, [0.89—1.01], (p = 0.031). This evidence concerns the gene CD8A and telangiectasis.