Nevertheless, we also noted that after myopia induction for 2 and 4 weeks, the expression of E-cadherin in the sclera in the LIM group was significantly higher than the level of the NC group, whereas the expression of TGF-β1 and COLI was continuously decreased (Fig. 9C, D, *P < 0.05 and **P < 0.01), indicating that the continuously elevated E-cadherin. The gene discussed is CDH1; the disease is myopia.