In contrast, the expression trend of the related molecules was reversed after 4 weeks of myopia induction (Fig. 9B, *P < 0.05, **P < 0.01, and ****P < 0.0001), suggesting that PIK3R3 and p-AKT2 may be correlated with cell survival and apoptosis. The gene discussed is AKT2; the disease is myopia.