Additionally, DCLRE1C is involved in V(D)J recombination in lymphocytes, which is a key process for immunological diversity and an enhanced adaptive immune response (Rohr et al., 2010), and DLL4 in the notch signaling pathway, in which it regulates the development of innate lymphoid cells, helps form secondary lymphoid organs, and helps remodel tissue after injury or infection, thus playing a central role in the innate immune response (Pellegrinet et al., 2011; Nauman and Stanley, 2022). This evidence concerns the gene DLL4 and infection.