Normal B and cancer 1 clusters shared inflammatory markers CCL2, TNFRSF12A, and IL1R1, pathways including TNFα, IL, and Myc signaling, and activity of inflammation, hypoxia, and lipid metabolism–associated transcription factors NFATC2, ARNT, PPARA, and PPARGC1A. The gene discussed is MYC; the disease is cancer.