KLK3 and posterior cortical atrophy: Early detection of PCa notonly improves patients’ life expectancy and overall qualityof life but also has the potential to reduce the financial burdenassociated with treatment for both patients and government entities.1,2 Early detection strategies using a prostate-specific antigen (PSA)as a PCa-specific biomarker have already been widely implemented,leading to increased success in early PCa diagnosis and a stage migrationphenomenon.