In various cancers, including malignant glioma, gastric cancer, salivary adenoid cystic carcinoma, and hepatocellular carcinoma (HCC), B7-H3 promotes epithelial-to-mesenchymal transition (EMT) via the activation of the JAK2/STAT3/Slug signaling pathway [43,44,45]. Here, JAK2 is linked to hepatocellular carcinoma.