Considering UNC13A confers risk for both ALS and FTD and the effect on the ALS phenotype is TDP‐43 driven, we hypothesized that homozygosity for the C‐allele at rs12608932 in UNC13A negatively impacts survival in TDP‐43 associated FTD. The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.