GSDMC was previously shown to be cleaved by Caspase‐6 and Caspase‐8 in vitro and was activated by Caspase‐8 but not by Caspase‐6 in breast cancer.[16] To investigate which Caspase protein might be responsible for GSDMC activation in colorectal cancer, we first analyzed the expression of various Caspase proteins in intestinal tumors. Here, GSDMC is linked to breast carcinoma.