Irradiated wild‐type (WT) recipients reconstituted with WT or Gsdmc2–4−/− bone marrow cells showed comparable tumor size (Figure 2F, left panel), tumor number, and tumor load (Figure 2G), suggesting that GSDMC in immune cells is dispensable for AOM‐DSS induced CRC progression. Here, GSDMC is linked to colorectal carcinoma.