Transcriptomic sequencing and enrichment analyses revealed the activation of cytokine‐related pathways, particularly the JAK‐STAT pathway, which is known to regulate immune responses in the tumor microenvironment.[47, 48] Western blot analysis confirmed JAK‐STAT pathway activation in DCs and macrophages, underscoring its critical role in reversing the immunosuppressive microenvironment of SCLC. The gene discussed is SOAT1; the disease is neoplasm.