TERT also regulates a plethora of key signaling pathways, namely Wnt/β‐catenin and NF‐κB, as well as metabolic genes involved in glycolysis and oxidative phosphorylation to meet the energy demands of cancer cells, while interacting with the PI3K/Akt pathway to further enhance cell survival and proliferation [4, 5]. The gene discussed is TERT; the disease is cancer.