KL and myelodysplastic syndrome: Sample-weighted multivariable linear regression models were used to examine the association between MDS and serum Klotho levels, adjusting for age, sex, race, socioeconomic status, lifestyle factors (smoking, alcohol use), clinical parameters (body mass index, blood pressure, lipid levels), and energy intake.<h4>Results</h4>The weighted average serum Klotho concentrations decreased significantly across MDS groups (low: 864.50, middle: 805.67, high: 755.02 pg./mL; <i>p</i> < 0.0001).