LEfSe analysis revealed that <i>Akkermansia, Lawsonibacter, Clostridium,</i> and <i>Neglectibacter</i> were significantly associated with EPO-induced AAA development, while <i>Lactobacillus, Alistipes, Limosilactobacillus,</i> and <i>Eisenbergiella</i> showed significant negative correlations. This evidence concerns the gene EPO and triple-A syndrome.