Glucose metabolism is regulated by oncogenic BRAF through hypoxia inducible factor 1 alpha (HIF-1 alpha), avian myelocytomatosis viral oncogene homolog (c-Myc), and microphthalmia-associated transcription factor (MITF), and BRAF-mutated melanomas exhibit increased glycolysis [27]. The gene discussed is MYC; the disease is melanoma.