Although several lncRNAs, such as HOX transcript antisense RNA (HOTAIR), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1; also known as nuclear-enriched abundant transcript 2—NEAT2), and smoking and cancer-associated lncRNA 1 (SCAL1; also referred to as lung cancer-associated transcript 1—LUCAT1), have been linked to the pathogenesis of lung cancer, the specific mechanisms and clinical advancements of lncRNA dysregulation in these neoplasms have not as yet been fully characterized [26–29]. This evidence concerns the gene MALAT1 and neoplasm.