ZNFX1 and lung cancer: qRT-PCR experiments demonstrated that 5-aza-2′ deoxycytidine (DAC);100 nM for 72 h), upregulated ZNFX1 in lung tumor cells while markedly abrogating CSC or ZFAS1 overexpression-mediated ZNFX1 repression in NREC and lung cancer cells (Fig. 6A; Supplementary Fig. S7).