NFKB1 and lung cancer: qChIP analysis demonstrated increased occupancy of NFkB-p65 in the ZFAS1 enhancer region in primary lung cancers relative to paired normal lung tissues; NFkB-p65 occupancy within the regulatory region of ZFAS1 was higher in cancer as well as normal lung tissues from smokers compared with never smokers (representative results depicted in Fig. 11D).