CYP19A1 and endometriosis: Futhermore, in the ovary, DCI treatment downregulated the expression of aromatase (Cyp19a1), the enzyme critical for estrogen biosynthesis, and increased the number of primordial to antral follicles, suggesting a beneficial effect on ovarian folliculogenesis.<h4>Conclusions</h4>By modulating proliferation, EMT transition and aromatase activity, DCI emerges as a promising compound for endometriosis treatment.