In females, the early atherosclerotic arterial-wall MP-dominant GRN174 involving regulation of immune responses was identified together with the advanced atherosclerosis arterial-wall MP-dominant GRN33 involving lipid-laden TREM2−/TREM1+-high and inflammatory macrophages and the EC and MP GRN122 involving endoMT. This evidence concerns the gene TREM1 and atherosclerosis.