PKA phosphorylation of PLIN1 was suppressed by more than 80% during 3-OHB infusion in both groups (participants with type 1 diabetes: median ratio 0.15; 95% CI 0.07, 0.31; p<0.001; control participants: median ratio 0.18; 95% CI 0.08, 0.38; p<0.001) (Fig. 6d). The gene discussed is PLIN1; the disease is type 1 diabetes mellitus.