MYCN and neoplasm: Administration of 2DG (50 μg/g) significantly reduced tumor weight and volume in the non-MYCN-amplified SK-N-AS and SK-N-FI groups, whereas treatment with ONC201 (50 μg/g) resulted in a significant increase in tumors and counteracted the inhibitory effect of 2DG on NB development, as illustrated in the tumor image (Fig. 1B) along with the quantification of weight and volume (Fig. 1C and D).