An early Italian trial randomised 39 adults with T2DM above 65 years old to either incretin (ie, the GLP-1RA liraglutide or several DPP-4is) or SGLT-2i therapy in addition to metformin and found no differences across cognitive tasks (all p>0.05, effect sizes not reported) at 1 year.89 Here, GCG is linked to type 2 diabetes mellitus.