SLC2A2 and gout: Moreover, in relation to previous findings showing an association between genetic variations in GLUT2/SLC2A2 and gout/serum urate (Table 1 and Fig. S1) (1, 4), our findings here suggest that GLUT2 might exert a physiological influence on urate handling, although whether and how GLUT2 is involved in the direct regulation of serum urate levels should be explored in future studies.