IL21 and laryngotracheoesophageal cleft: We have previously found enhanced protein levels of TNF-α in CC and UC, IL-6 in CC and IL-21 in both CC and LC patients as well as increased mRNA levels of IL-6 and IL-21 in MC and UC patients.28 The disparity between our previous and current results may be due to the use of different Luminex kits from different manufacturers.