Through the release of cytotoxic molecules, such as perforin and granzyme B, as well as the interaction of Fas with Fas ligand (FasL), CD8+ T cells can exert many detrimental effects on tumor cells.8 There is limited information regarding these cytotoxic molecules and the possible roles of CD8+ T cells in MC, hence further research is necessary. The gene discussed is CD8A; the disease is neoplasm.