The median urine LRG1 concentration in the uncomplicated appendicitis group was 0.10 (IQR 0.02–0.29) μg/mL, which is significantly lower than in the no appendicitis group (0.33 [0.10–0.72] μg/mL) and in the complicated appendicitis group (0.29 [0.12–1.07] μg/mL), p < 0.001 (Table 1, Fig. 2a and b). The gene discussed is LRG1; the disease is appendicitis.