SQSTM1 variants are associated to frontotemporal dementia and/or amyotrophic lateral sclerosis-3 (FTDALS3, MIM #616437) while RORA alterations are associated to intellectual developmental disorder with or without epilepsy or cerebellar ataxia (IDDECA, MIM #618060). The gene discussed is SQSTM1; the disease is cerebellar ataxia.