SIRPA and neoplasm: Using eight groups of mouse xenograft models, we established PD1, SIRPα, dual-drug, radiation + PD1, radiation + SIRPα, radiation + dual-drug, radiation, and control groups, with specific intervention time points as shown in Fig. 5A. Tumor growth was monitored every other day starting from Day 1 by measuring both the long and short diameters of the tumors to roughly estimate the tumor area (Fig. 5B).