Upon surveying the available data for LGG (brain lower grade glioma), HNSC, KIRC, SARC (sarcoma), LIHC (liver hepatocellular carcinoma), UCEC, and LUSC (lung squamous cell carcinoma), the expression of ISG15 exhibited a positive correlation with ISG15 loss (Supplementary Table S1). This evidence concerns the gene ISG15 and sarcoma.