(D) Immunoflourescent and in situ hybridization localization of PASMC (ACTA2, RGS5, and IGFBP5) and PAAF markers (PDGFRA, ADH1C, CFD, and SCARA5) in IPAH human lungs (n = 5). The gene discussed is PDGFRA; the disease is idiopathic pulmonary arterial hypertension.