Finally, RT-qPCR expression of MX1, LY6E, IFI44 and OASL was consistent with the results of the dataset.<h4>Conclusion</h4>MX1, LY6E, IFI44 and OASL were identified as biomarkers related to TEX in SLE. Here, OASL is linked to systemic lupus erythematosus.