The relationship between EEG severity in the acute phase and disease severity, treatment response, and prognosis was examined to identify factors contributing to poor outcomes.<h4>Results</h4>The cohort included 60 patients with the following subtypes of encephalitis: anti-LGI1 (22), anti-NMDAR (12), anti-GABA<sub>B</sub>R (7), anti-GAD65 (6), anti-MOG (7), anti-Caspr2 (4), and GFAP-A (2). The gene discussed is CNTNAP2; the disease is encephalitis.