Specifically, we attempted to determine whether high AFP (> 1,000ng/ml) and other potentially relevant factors affect survivals of patients with BCLC stage 0 HCC after LR.<h4>Methods</h4>This retrospective study focused on 223 patients who received LR for stage 0 HCC of BCLC between 2004 and 2012. The gene discussed is AFP; the disease is hepatocellular carcinoma.