In the current study, we analyzed the RNA and protein expression of CD70, using RNAscope and immunofluorescence (IF) and the protein expression of its receptor, CD27, including its correlation with CD45 + CD8 + immune cell infiltration previously reported in [13] on a large, real-word cohort of early-stage SCLC patients. The gene discussed is CD8A; the disease is small cell lung carcinoma.