DNER and neoplasm: The bromodomain and extraterminal domain (BET) protein family, including BRD2, BRD3, BRD4, and BRDT, comprises epigenetic readers that regulate gene transcription by binding to acetylated lysine residues on histones and master transcriptional factors.1, 2, 3, 4, 5 BET proteins may be involved in pathological conditions, including tumor development.6