Macrophages are central to the pathogenesis and progression of atherosclerosis due to their capacity to initiate and sustain inflammatory and immune responses.[19] In particular, the macrophage‐mediated activation of these responses constitutes a critical mechanism in the evolution of atherosclerotic lesions.[20] Therefore, we selected the “inflammatory response” term in GO analysis for further investigation and considered that WEE1 knockout may affect oxLDL‐induced inflammation and immune response in macrophages. This evidence concerns the gene WEE1 and atherosclerosis.