DLD and cancer: Inhibiting the TCA cycle or the ETC could both mitigate ferroptosis.[169] Additionally, the fact that glutaminolysis or other regulators such as dihydrolipoamide dehydrogenase (DLD), focal adhesion kinase (FAK) and COX7A1 fuel the TCA cycle to potentiate ferroptosis in different cancers further substantiates this perspective.[157, 170] Like ferroptosis, cuproptosis can also influence the TCA cycle conversely.