Results showed PCOS patients had significantly higher levels of DEP and DBP than those in control group (p < 0.05). Meanwhile, the levels of DBP, DEP, and DEHP declined in sequence in PCOS women. But no statistically significant difference in DEHP level was noted between these 2 groups (p = 0.853); in the PCOS patients, there was no significant correlation between the serum levels of 3 phthalate esters (DBP, DEP, and DEHP) and estradiol, TST, FSH, LH, prolactin, BMI, and age. The gene discussed is BRD2; the disease is polycystic ovary syndrome.