Serum BPE, BPC, BPG, BPM, BPP, BPZ, BPFL and BPBP concentrations did not differ significantly between PCOS and control subjects. Women whose serum BPM and BPP concentrations were in the highest tertile were more likely to be PCOS diagnosed with PCOS (adjusted OR = 0.43 [95% Cl 0.20–0.89], p < 0.001 and 0.56 [95% Cl: 0.27–0.96], p = 0.049, respectively). Here, SRPX2 is linked to polycystic ovary syndrome.