[32] assessed the antiangiogenic effects of PG juice (3% and 6%) up to 48 h, in the context of multiple myeloma (MM), using human brain microvascular endothelial cells and several MM cell lines; an inhibitory effect on the tube formation and endothelial cell migration was recorded along with a decreased expression in several angiogenic genes (e.g., MMP2 and VEGF). The gene discussed is MMP2; the disease is plasma cell myeloma.