Patients had fatigue despite increased appetite and excess weight loss (the mean body mass index (BMI) of 22.19 ± 1.13 kg/m2 (20.72–24.56), and the mean percentage excess BMI loss (%EBMIL) of 123.26 ± 14.85% (102.53–163.55) after initial surgery), generalized or pretibial edema accompanying hypoalbuminemia (mean albumin of 2.7 ± 0.52 mg/dL (1.9–3.8)) with other nutritional parameters, like Hb, iron, vitamin B12, folic acid, zinc, calcium, 25 (OH) vitamin D, parathormone, creatinine, and glomerular filtration rate (GFR), out of normal ranges in some of the patients. The gene discussed is GSTM1; the disease is Hypoalbuminemia.