Significant improvement in the delayed recall tasks of memory scores, however there were not significant differences for the total recall task of the memory scores, the subjective cognitive complaints nor in the concentration of BDNF.Despite no observed differences in BDNF levels or subjective cognitive impairment, the intervention, based on individualized education and counseling using telephone and social media, positively impacted memory function. Here, BDNF is linked to Cognitive impairment.