Genetic variants at the IL13RA1 locus were also associated with BMI in the Genetic Investigation of Anthropomorphic Traits (GIANT) Consortium (a multiethnic group composed of 62.2% European, 16.4% Hispanic/Latin American, 15.3% Asian, and 6.1% African American/Afro-Caribbean individuals, Figure 6A) (48); however, the same locus was not associated with T2D in the predominately European population (data not shown) (49). This evidence concerns the gene IL13RA1 and type 2 diabetes mellitus.