Flow cytometry analysis confirmed that CD84 is upregulated in primary AML samples obtained from different sources (n = 31) (Figure 1D) and AML cell lines (n = 9) (Supplemental Figure 1B) compared with levels in healthy donor CD34+ cells (n = 5) (Figure 1, E and F), independent of disease status or cytogenetic abnormalities (Supplemental Table 2). This evidence concerns the gene CD84 and acute myeloid leukemia.