ITGA6 and aortic aneurysm: To clarify the role of ITGA6 in aortic aneurysm, we injected lentivirus vector encoding negative shRNA control (Lenti-shNC) or lentivirus vector encoding shRNA targeting Itga6 (Lenti-shItga6) with 2 reverse loxP sites, which can be recognized by Cre recombinase.